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Brooker R. Concepts of Genetics
McGraw-Hill, 2012. - 804 p. - This textbook emphasizes a large number of these mode approaches. For example, new technologies have made it possible to produce medicines that would otherwise be difficult or impossible to make. An example is human recombinant insulin, sold under the brand name Humulin, which is synthesized in strains of Escherichia coli bacteria that have been genetically altered by the addition of genes that encode the functional regions of human insulin. The bacteria are grown in a laboratory and make large amounts of human insulin, which is purified and adminis-tered to millions of people with insulin-dependent diabetes. Chapter 20 describes the production of insulin in greater detail and also examines other ways that genetic approaches have applications in the area of biotechnology.
Contents
NTRODUCTION
Overview of Genetics
PATTERNS OF INHERITANCE
Reproduction and Chromosome Transmission
Mendelian Inheritance
Sex Determination and Sex Chromosomes
Extensions of Mendelian Inheritance
Extranuclear Inheritance, Imprinting, and Mateal Effect
Genetic Linkage and Mapping in Eukaryotes
ariation in Chromosome Structure and Number
Genetics of Bacteria
Genetics of Viruses
MOLECULAR STRUCTURE AND REPLICATION OF THE GENETIC MATERIAL
Molecular Structure of DNA and RNA
Molecular Structure and Organization of Chromosomes
DNA Replication and Recombination
MOLECULAR PROPERTIES OF GENES
Gene Transcription and RNA Modification
Translation of mRNA
Gene Regulation in Bacteria
Gene Regulation in Eukaryotes
Gene Mutation and DNA Repair
GENETIC TECHNOLOGIES
Recombinant DNA Technology
Biotechnology
Genomics I: Analysis of DNA and Transposable Elements
Genomics II: Functional Genomics, Proteomics, and Bioinformatics
GENETIC ANALYSIS OF INDIVIDUALS AND POPULATIONS
Medical Genetics and Cancer
Developmental Genetics and Immunogenetics
Population Genetics
Quantitative Genetics
Evolutionary Genetics
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