Nicolaou K.C., Sorensen E.J. (eds.) Classics in Total Synthesis. Targets, Strategies, Methods

формат djvu
размер 9.33 МБ
добавлен 22 сентября 2011 г.

VCH. 1996. 827 p.

This book is a must for every synthetic chemist. With didactic skill and clarity, K. C. Nicolaou and E. Sorensen present the most remarkable and ingenious total syntheses from outstanding synthetic organic chemists.

To make the complex strategies more accessible, especially to the novice, each total synthesis is analyzed retrosynthetically. The authors then carefully explain each synthetic step and give hints on alteative methods and potential pitfalls. Numerous references to useful reviews and the original literature make this book an indispensable source of further information.

Special emphasis is placed on the skillful use of graphics and schemes: Retrosynthetic analyses, reaction sequences, and stereochemically crucial steps are presented in boxed sections within the text. For easy reference, key intermediates are also shown in the margins.

Graduate students and researchers alike will find this book a gold mine of useful information essential for their daily work. Every synthetic organic chemist will want to have a copy on his or her desk.

Contents

Introduction: Constructing the Molecules of Nature
Strychnine
Penicillin V
Reserpine
Prostaglandin F2a (PGF2a) and Prostaglandin E2 (PGE2)
Progesterone
Carpanone
Vitamin B12
Prostaglandin A2 (PGA2) and Prostaglandin F2a (PGF2a)
Estrone
Erythronolide B
Monensin
Periplanone B
Isocomene
Monensin
Thienamycin
Endiandric Acids A-D
Biotin
l-Hexoses
Asteltoxin
Periplanone B
Menthol
Hirsutene and delta9(12)-carpnellene
Amphoteronolide B and Amphotericin B
Ginkgolide B
Methyl Homosecodaphniphyllate
Indolizomycin
Cytovaricin
Gilvocarcin M and Gilvocarcin V
Calicheamicin gammaII
Rapamycin
Paeoniflorigenin and Paeoniflorin
Strychnine
Taxol
Zaragozic Acid A/Squalestatin S1
Palytoxin
Brevetoxin B

Похожие разделы

Смотрите также

ApSimon J. (ed.) The Total Synthesis of Natural Products. V.6

формат pdf
размер 11.32 МБ
добавлен 12 марта 2011 г.

Wiley. 1984. 269 p. The Total Synthesis of Aromatic Steroids 1972-1981 Gene Synthesis The Total Synthesis of Triterpenes 1973-1981 The Total Synthesis of Carbohydrates 1972-1980 The Total Synthesis of Pyrrole Pigments 1973-1980 Index

ApSimon J. (ed.) The Total Synthesis of Natural Products. V.7

формат pdf
размер 18.4 МБ
добавлен 12 марта 2011 г.

Wiley. 1988. 473 p. The Total Synthesis of Macrocyclic Lactones Synthesis of the Leukotrienes The Synthesis of Monoterpenes, 1980-1986 Index

General and Synthetic Methods. Vol.06

формат pdf
размер 29.52 МБ
добавлен 13 марта 2011 г.

Chemical Society. 1983. 434 p. Saturated and Unsaturated Hydrocarbons Aldehydes and Ketones Carboxilic Acids and Derivatives Alcohols, Halogeno-compounds, and Ethers Amines, Nitriles, and Other Nutrogen-containing Functional Groups Organometallics in Synthesis Saturated Carbocyclic Ring Synthesis Saturated Heterocyclic Ring Synthesis Highlights in Total Synthesis of Natural Products Reviews on General Synthetic Methods

General and Synthetic Methods. Vol.07

формат pdf
размер 23.65 МБ
добавлен 13 марта 2011 г.

Chemical Society. 1985. 488 p. Saturated and Unsaturated Hydrocarbons Aldehydes and Ketones Carboxilic Acids and Derivatives Alcohols, Halogeno-compounds, and Ethers Amines, Nitriles, and Other Nutrogen-containing Functional Groups Organometallics in Synthesis Saturated Carbocyclic Ring Synthesis Saturated Heterocyclic Ring Synthesis Highlights in Total Synthesis of Natural Products Reviews on General Synthetic Methods

General and Synthetic Methods. Vol.08

формат pdf
размер 26.27 МБ
добавлен 13 марта 2011 г.

Chemical Society. 1986. 588 p. Saturated and Unsaturated Hydrocarbons Aldehydes and Ketones Carboxylic Acids and Derivatives Alcohols, Halogeno-compounds, and Ethers Amines, Nitriles, and Other Nutrogen-containing Functional Groups Organometallics in Synthesis Saturated Carbocyclic Ring Synthesis Saturated Heterocyclic Ring Synthesis Highlights in Total Synthesis of Natural Products Reviews on General and Synthetic Methods

General and Synthetic Methods. Vol.14

формат pdf
размер 25.6 МБ
добавлен 13 марта 2011 г.

Chemical Society. 1992. 452 p. Saturated and Unsaturated Hydrocarbons Aldehydes and Ketones Carboxylic Acids and Derivatives Alcohols, Halogeno-compounds, and Ethers Amines, Nitriles, and Other Nutrogen-containing Functional Groups Organometallics in Synthesis Saturated Carbocyclic Ring Synthesis Saturated Heterocyclic Ring Synthesis Highlights in Total Synthesis of Natural Products Reviews on General and Synthetic Methods

General and Synthetic Methods. Vol.15

формат pdf
размер 22.41 МБ
добавлен 13 марта 2011 г.

Chemical Society. 1993. 468 p. Saturated and Unsaturated Hydrocarbons Aldehydes and Ketones Alcohols, Halogeno Compounds, and Ethers Amines, Nitriles, and Other Nutrogen-containing Functional Groups Organometallics in Synthesis Saturated Carbocyclic Ring Synthesis Saturated Heterocyclic Ring Synthesis Highlights in Total Synthesis of Natural Products Reviews on General and Synthetic Methods

General and Synthetic Methods. Vol.16

формат pdf
размер 24.7 МБ
добавлен 13 марта 2011 г.

Chemical Society. 1994. 620 p. Saturated and Unsaturated Hydrocarbons Aldehydes and Ketones Carboxylic Acids and Derivatives Alcohols, Halogeno Compounds, and Ethers Amines, Nitriles, and Other Nutrogen-containing Functional Groups Organometallics in Synthesis Saturated Carbocyclic Ring Synthesis Saturated Heterocyclic Ring Synthesis Highlights in Total Synthesis of Natural Products Reviews on General and Synthetic Methods

Hart D.J. Organic Synthesis via Examination of Selected Natural Products

формат pdf
размер 4.93 МБ
добавлен 10 ноября 2011 г.

World Scientific Publishing Co. 2011. 566 p. This book is written for advanced graduate and undergraduate students to expose them to a variety of strategies for the synthesis of organic compounds. This is done largely within the context of natural products synthesis, but some unnatural products synthesis is also included. Multiple approaches to each group of synthesis targets are presented, and the approaches are compared with one another with a...

Levy D.E., Fuegedi P. (eds.) Organic Chemistry of Sugars

формат pdf
размер 27.58 МБ
добавлен 30 сентября 2011 г.

CRC Taylor & Francis. 2006. 870 p. Intrigued as much by its complex nature as by its outsider status in traditional organic chemistry, the editors of The Organic Chemistry of Sugars compile a groundbreaking resource in carbohydrate chemistry that illustrates the ease at which sugars can be manipulated in a variety of organic reactions. Each chapter contains numerous examples demonstrating the methods and strategies that apply mainstream orga...