10th Ed. 2009, 966 pages. Jones and Bartlett Publishers, ISBN:
978-7-04-026961-1
Фундаментальное руководство по молекулярной биологии и генетике,
содержащее четкое, полное и ясное изложение современных
представлений о структуре генов, организации генома про- и
эукариот, механизме синтеза белка и регуляции экспрессии генов, а
также о мобильных элементах генома и перестройках ДНК.
The field of molecular biology and molecular genetics is rapidly
changing with new data acquired daily and new insights into
well-studied processes presented on a scale of weeks or months
rather than years. For decades Lewin's GENES has provided the
teaching community with the most cutting edge presentation of
molecular biology and molecular genetics, covering gene structure,
sequencing, organization, and expression. The latest edition, with
a knowledgeable new author team, has enlisted 21 scientists to
provide revisions and content updates in their individual fields of
expertise, ensuring that Lewin's GENES X is the most current and
comprehensive text in the field. Informative new chapters, as well
as a reorganization of material, provide a more logical flow of
topics and many chapters have been renamed to better indicate their
contents. Lewin's GENES X also contains new pedagogical features to
help students lea as they read and an online student study guide
allows students to test themselves on key material.
Contents
Genes Are DNA
Genes Code for Proteins
Methods in Molecular Biology and Genetic Engineering
The Interrupted Gene
The Content of the Genome
Genome Sequences and Gene Numbers
Clusters and Repeats
Genome Evolution
Chromosomes
Chromatin
The Replicon
Extrachromosomal Replicons
Bacterial Replication Is Connected to the Cell Cycle
DNA Replication
Homologous and Site-Specific Recombination
Repair Systems
Transposable Elements and Retroviruses
Somatic Recombination and Hypermutation in the Immune System
Prokaryotic Transcription
Eukaryotic Transcription
RNA Splicing and Processing
mRNA Stability and Localization
Catalytic RNA
Translation
Using the Genetic Code
The Operon
Phage Strategies
Eukaryotic Transcription Regulation
Epigenetic Effects Are Inherited
Regulatory RNA
Glossary
Index
Contents
Genes Are DNA
Genes Code for Proteins
Methods in Molecular Biology and Genetic Engineering
The Interrupted Gene
The Content of the Genome
Genome Sequences and Gene Numbers
Clusters and Repeats
Genome Evolution
Chromosomes
Chromatin
The Replicon
Extrachromosomal Replicons
Bacterial Replication Is Connected to the Cell Cycle
DNA Replication
Homologous and Site-Specific Recombination
Repair Systems
Transposable Elements and Retroviruses
Somatic Recombination and Hypermutation in the Immune System
Prokaryotic Transcription
Eukaryotic Transcription
RNA Splicing and Processing
mRNA Stability and Localization
Catalytic RNA
Translation
Using the Genetic Code
The Operon
Phage Strategies
Eukaryotic Transcription Regulation
Epigenetic Effects Are Inherited
Regulatory RNA
Glossary
Index