Springer, 2009. - 451 p. - This FISH application guide provides an
overview of the principles and the basic techniques of fluorescence
in situ hybridization (FISH) and primed in situ hybridization
(PRINS), which are successfully used to study many aspects of
genomic behavior and alterations. In 36 chapters, contributed by
inteational experts in their particular field, the nowadays
multiple approaches and applications of the powerful techniques are
presented and detailed protocols are given. Described here are
methods using various cell types and tissues as well as different
organisms, such as mammalians, insects, plants and microorganisms.
Multicolor FISH procedures and special applications such as the
characterization of marker chromosomes, breakpoints, cryptic
aberrations, nuclear architecture and epigenetic changes, as well
as (array-based) comparative genomic hybridization studies are
presented. Overall, the technique of choice is introduced for
single cell analysis in human genetics, microbiology, animal and
plant sciences.
Liehr T. Fluorescence In Situ Hybridization (FISH) - Application Guide
- формат pdf
- размер 4.64 МБ
- добавлен 20 января 2012 г.
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