
CHAPTER
5
Central
Intr
av
enous
Thera~
y
__
---,-
--",-,
cccccccc=-c,OCC""
,,-hm
,'~i",
lha,
a"
=,,,,d
u,'
1.1<
thin",)'
ik>';C<J
/0"
,"'ir
;nl'8,il)'; and
I.
V.
wI",ion
infuu.
inlo
,u"".oo
ing
,i"",,.
A gre>!
ItIlIny
pII
. rmacologic
'gon"
are admini.l<red intra'..,ooo.Jy
lru.1
are
""sic.,.",
V
<Mea
n
's:,,,,
.gen"
thaI
mayc.u,",
blisterin
g.'
Thu
••
",ic.n"
COIl
c. u
..
significanl venou.
irri~ion
that lypic.lly
i.
'""'"
pronooncNl in .ltIlIller
",
...
1 •.
Ve.icOll"
""'y
cause infl. mmalory change.
in
.m
. ller ,..,,,el
•.
> condilion ",ferred
to
""
plll.
bi'
..
. • Phlobt,i.
o.u.
,
,,
"'"
only pain
.nd
di""""fort
fo.-
the palienl.
but
it
.150 can rompromi
..
the integrily
of
venou. acee
..
. nd palmcy
of
I,
V,
flow.
n.ere
are many pII"""",,ologic
'gon"
th
..
are
,-",ic""".
bu, :rome
.ig
nific.nl general
c
...
gori
..
include chemotherapeutic
.genu
and
vuopre...,...
(e,g
..
dopamine).
n.e
deli>ory
of
,oW
paren",""
nutrie"' ",Iulions via the peripheral roote
.1",
can
c.u'"
pIIlebt'i •. 1herefore. another common iooic
..
ion to init
i>!e
""ntral
LV
.
lher2p)'
in • paticnl is to
deli,
..
r nutrilion.lly romp/o,e pa!<nl<ral "Ulrition.
Nutritional
",
Iut
ion,
deli,-cre<!
by
the central
LV
. roole
""'y
include tot. 1 pa!<nl<ral
"Ulrition (TPN), in'ravenou. fat emul
.ions
(IVFE..),.nd
tot.1 nUI""nl admix,ure.
(fNk).
which are
disru»ed
in more detail in Choptcr /0,
Central Venous Access Routes
There
.""",
..
ral
routo.
by"
hich cemral
ve
i
ns
migh'
be
",,,,,.sed by
I,
V,
line.,
which""""
com...,.,ly
u'"
.peci.lly
de.igr>ed
LV
. c.thetors,
II
i.
p"'.
ible
to
thread
• Icnglhy 1 V. c
..
heler by • peripheral
aoc=
.il
e in'o • cent
""
",in.
n.e
..
type.
of
peripherally
""""
"00
""ntral
c.thete"
are referred to
..
pmphmlll)'
insmro
",",rat
ro,h"".
(PICC
.),·
I n""nion
of
Pice
. does
not
cany
the risk>
of
hen-cIllo."
0.-
pneurnothon'
....
1 might occur when
",nlral
.i
te
••
re
rued
fo.-
""nl",1
,-<
.......
access, Other venou.
or"""
.i'e.
are ",nl",1 and commonly ioclude lhe
.u
bel
..
i""
ve
in and inl<rn.1 jugular ,..,in and
Ie
..
commonly the e<lcrnaI jugular vein and
femor:al ,..,in.' Theexrem.1 jugular ,..,in tend.
10
be
a I
...
".b
le . i
le
than lbe intom.1
jugul
",
""in
0<
the
",bel"ian
ve
in and
therefou
i.
not.
preferred
fi"'
_line
I''lle
access ,
...
",1, The
fomonl
acee
..
roore rends
10
cany
gre>1or
ri.k.
fo.-
"'plicemi.
gi,
..
n its proximily
10
the
anu,
and urelhral ori6
ce
and therefore
i.
0
100
00< as
prefo",bl
e.
fi"'
_line ,..,
...
1 as the inlernal iUglll", vein
.nd
. ubel.vian ,..,in, Con,,,,1
I,V,
l
ine.
that are acee.sed by conlral sire.ltIlIy ioch
....
tunnel
Nl
cenlr.l!
,-ellOO'
c. thet.B. percul2J>eoo. cen,,,,1 ><Il00. c
..
here".
and impl>ntNl port,. Each
of
the
..
will be disrus>ed in the following sertion •.