Proceedings of the NATO Advanced Study Institute on Optical
Chemical Sensors (Erice, Italy, 29 July - 10 August 2004).
Springer, 2006. 549 p. ISBN-10 1-4020-4609-X
In the summer of 2004, the NATO A.S.I. on the subject Optical Chemical Sensors was organised in Erice, Sicily. This NATO A.S.I. was the 40th Course of the Inteational School of Quantum Electronics, under the auspices of the Ettore Majorana Foundation and Center for Scientific Culture and was directed by Dr. J. Homola of the Institute of Radio Engineering and Electronic (IREE) of the Academy of Sciences in Prague and by Dr. F.Baldini of the Nello Carrara Institute of Applied Physics (IFAC-CNR). It is also the fourth course in the framework of the ASCOS (Advanced Study Course on Optical Chemical Sensors) series, founded in 1999 by Prof. Otto Wolfbeis. This book presents the Proceedings of this advanced course providing a deep overview of both the fundamentals of optical chemical sensing and the applications of chemical sensors.
The objective of the NATO A.S.I. was to bring together bright young (future) scientists, coming from all imaginable fields of expertise related to optical chemical sensors, to lea from selected researchers and from each other in an appropriate atmosphere. The course covered all the principal optical chemical sensor technologies and related fields and provided a platform to exchange ideas and experience. The objective was accomplished through teaching theory and basics on a level every participant could follow and then giving the participant an opportunity to apply the gained knowledge.
The quality of the course was assured by the presence of 27 lecturers, key specialists for each topic, coming from 13 different countries (12 European countries plus the USA).
An outstanding presence was assured by Prof. Charles Townes, one of the inventors of the laser, who was invited in occasion of the forty-year celebration of the Nobel Prize award in Physics for the discovery of the laser. His lecture during the ceremony was one of the most exciting moments of the Course; it was focused on an historical re-examination of the invention of the laser and a discussion of the bases and principles which can guide additional research activity.
The chapters in these Proceedings follow for the most part the chronology of the NATO A.S.I. The first section is devoted to the fundamental aspects of optical chemical sensing. All the spectroscopic techniques utilised in chemical sensing are described (absorption, fluorescence, chemiluminescence, Raman spectroscopy, surface plasmon resonance) as well as the main chemical aspects conceing the sensing mechanism and/or the identification of the proper chemical transducer (enzyme-based reactions, antibody/antigen interaction, ) and its immobilisation on the most suitable support (polymers, sol-gel, covalent bond). After this first section, attention is given to sensor applications with chapters focused on the different areas in which optical sensors find their utilisation (detection of bioterrorist threats, food safety, invasive applications in medicine, cultural heritage, gas sensing, the optical nose, DNA protein and sensor arrays, etc. ). On this basis we grouped the chapters in two main topics: fundamentals of optical chemical sensing and applications of optical chemical sensing.
By way of introduction, these two sections are preceded by the lecture of Prof. Townes on the birth of laser and maser and by a retrospective vision of optical chemical sensors of Prof. Wolfbeis.
Preface.
List of contributors.
Directors’s list of participants.
Editorial.
List of ISQE courses.
Birth of the maser and laser.
Fiber optic chemical sensors and biosensors: a view back.
Fundamentals of optical chemical sensing.
Fundamentals of optoelectronics.
Optical fibres for optical sensing.
Absorption-based sensors.
Fluorescence-based sensors.
Vibrational spectroscopic sensors.
Chemiluminescence-based sensors.
Sensors based on spectroscopy of guided waves.
Planar optical sensors and evanescent wave effects.
Interferometry in bio- and chemosensing.
Surface-enhanced Raman scattering.
Planar waveguiding systems for optical sensing.
Ultracompact optical sensors based on high index-contrast photonic structures.
Polymers in optical sensors.
Fundamentals of enzyme-based sensors.
Sol-gels for optical sensors.
Methods for attachment of antibodies onto optical biosensors.
Applications of optical chemical sensing.
The optical nose.
Invasive sensors in medicine.
Biosensors for detection of bioterrorist threats.
Review of methods of optical gas.
DNA and protein sensor arrays.
Sensors for food safety and security.
Optical chemical sensors for cultural heritage.
Index.
In the summer of 2004, the NATO A.S.I. on the subject Optical Chemical Sensors was organised in Erice, Sicily. This NATO A.S.I. was the 40th Course of the Inteational School of Quantum Electronics, under the auspices of the Ettore Majorana Foundation and Center for Scientific Culture and was directed by Dr. J. Homola of the Institute of Radio Engineering and Electronic (IREE) of the Academy of Sciences in Prague and by Dr. F.Baldini of the Nello Carrara Institute of Applied Physics (IFAC-CNR). It is also the fourth course in the framework of the ASCOS (Advanced Study Course on Optical Chemical Sensors) series, founded in 1999 by Prof. Otto Wolfbeis. This book presents the Proceedings of this advanced course providing a deep overview of both the fundamentals of optical chemical sensing and the applications of chemical sensors.
The objective of the NATO A.S.I. was to bring together bright young (future) scientists, coming from all imaginable fields of expertise related to optical chemical sensors, to lea from selected researchers and from each other in an appropriate atmosphere. The course covered all the principal optical chemical sensor technologies and related fields and provided a platform to exchange ideas and experience. The objective was accomplished through teaching theory and basics on a level every participant could follow and then giving the participant an opportunity to apply the gained knowledge.
The quality of the course was assured by the presence of 27 lecturers, key specialists for each topic, coming from 13 different countries (12 European countries plus the USA).
An outstanding presence was assured by Prof. Charles Townes, one of the inventors of the laser, who was invited in occasion of the forty-year celebration of the Nobel Prize award in Physics for the discovery of the laser. His lecture during the ceremony was one of the most exciting moments of the Course; it was focused on an historical re-examination of the invention of the laser and a discussion of the bases and principles which can guide additional research activity.
The chapters in these Proceedings follow for the most part the chronology of the NATO A.S.I. The first section is devoted to the fundamental aspects of optical chemical sensing. All the spectroscopic techniques utilised in chemical sensing are described (absorption, fluorescence, chemiluminescence, Raman spectroscopy, surface plasmon resonance) as well as the main chemical aspects conceing the sensing mechanism and/or the identification of the proper chemical transducer (enzyme-based reactions, antibody/antigen interaction, ) and its immobilisation on the most suitable support (polymers, sol-gel, covalent bond). After this first section, attention is given to sensor applications with chapters focused on the different areas in which optical sensors find their utilisation (detection of bioterrorist threats, food safety, invasive applications in medicine, cultural heritage, gas sensing, the optical nose, DNA protein and sensor arrays, etc. ). On this basis we grouped the chapters in two main topics: fundamentals of optical chemical sensing and applications of optical chemical sensing.
By way of introduction, these two sections are preceded by the lecture of Prof. Townes on the birth of laser and maser and by a retrospective vision of optical chemical sensors of Prof. Wolfbeis.
Preface.
List of contributors.
Directors’s list of participants.
Editorial.
List of ISQE courses.
Birth of the maser and laser.
Fiber optic chemical sensors and biosensors: a view back.
Fundamentals of optical chemical sensing.
Fundamentals of optoelectronics.
Optical fibres for optical sensing.
Absorption-based sensors.
Fluorescence-based sensors.
Vibrational spectroscopic sensors.
Chemiluminescence-based sensors.
Sensors based on spectroscopy of guided waves.
Planar optical sensors and evanescent wave effects.
Interferometry in bio- and chemosensing.
Surface-enhanced Raman scattering.
Planar waveguiding systems for optical sensing.
Ultracompact optical sensors based on high index-contrast photonic structures.
Polymers in optical sensors.
Fundamentals of enzyme-based sensors.
Sol-gels for optical sensors.
Methods for attachment of antibodies onto optical biosensors.
Applications of optical chemical sensing.
The optical nose.
Invasive sensors in medicine.
Biosensors for detection of bioterrorist threats.
Review of methods of optical gas.
DNA and protein sensor arrays.
Sensors for food safety and security.
Optical chemical sensors for cultural heritage.
Index.