Health Promotion 193
derstanding why it is that a substantial number of the participants who showed
mild to moderate stages of Alzheimer’s disease pathology in postmortem exami-
nations showed no symptoms of cognitive impairment prior to their death. The
study suggests that it is possible to resist the genetic and pathological forces of
Alzheimer’s disease through lifestyle and environmental changes.
The Nun Study found that heart disease and stroke significantly increased a
person’s risk for dementia, and that the brain infarcts caused by strokes seem to
“trip a switch,” making the developing of dementia much more likely. Snowdon
(2003) noted other conditions that may overwhelm the brain and trigger the clin-
ical onset of Alzheimer’s symptoms: brain trauma, depression, metabolic abnor-
malities, and specific nutritional deficits. Other researchers have found that
cardiovascular risk factors such as high cholesterol, high blood pressure, smok-
ing, and diabetes can also produce an increased risk of cognitive impairment
(Almeida, Norman, Hankey, Jamrozik, & Flicker, 2006).
The greatest protective factors associated with the prevention of dementia and
the development of the symptoms related to Alzheimer’s disease are social en-
gagement, intellectual engagement, and educational background. The Nun Study,
as well as the work of others, has shown conclusively that the higher the level of
schooling, the lower the risk of developing Alzheimer’s disease (Raiha, Kaprio,
Koskenvuo, Rajala, & Sourander, 1998; Rundek & Bennett, 2006; Snowdon, 2001).
Routine engagement in cognitively stimulating leisure activities over one’s life-
time, continuing into older adulthood, is strongly associated with a reduced risk
of Alzheimer’s disease (Wilson et al., 2002).
Regular social engagement is proven to reduce a person’s overall mortality and
risk for significant losses in cognitive functioning. In general, people who are
married live longer than unmarried people, and people who are active members
of religious or civic organizations live longer than people without such group af-
filiations (Rowe & Kahn, 1998). Although it is important to older adults to feel
connected and involved with their immediate and extended families, research
shows that social activities outside of the family may have a bigger impact on cog-
nitive function than social contacts with family (Glei et al., 2005).
Several studies have found a clear link between physical activity and lower
risks of cognitive impairment. The MacArthur Study reported that older men and
women were more likely to maintain high cognitive capacity when they engaged
in vigorous physical activity. A potential explanation was found in laboratory ex-
perimentation measuring the effects of exercise on the brains of rats. Increased ex-
ercise corresponded with increases in a nerve growth factor that promoted new
brain cell growth (Rowe & Kahn, 1998). A study of over 18,000 women found that
those who participate in regular moderate physical activity showed significantly
better cognitive function than inactive women, and another study found that older
men who walk more are less likely to develop dementia, including Alzheimer’s
disease (Center for the Advancement of Health, 2006).
E
VIDENCE
-B
ASED
P
RACTICE
G
UIDELINES
The well-known saying “Use it or lose it” applies to the brain and cognitive func-
tion just as much as it does to the rest of the body. Older adults should be encour-
aged to participate in an active lifestyle that includes frequent participation in
a wide range of cognitively, physically, and socially engaging and challenging