
149 
now  the spike tends to a point  in 
R 
that maximizes the distance function. 
In contrast, for 
D 
>> 
1, 
the motion of  a one-spike solution is proportional 
to the gradient of the regular part of the Neumann Green’s function for the 
Laplacian.  Finally, for 
D 
= 
0(1), 
the motion of 
a 
spike is proportional to 
the gradient of  the regular part of the reduced wave Green’s function. This 
second Green’s function depends on 
D. 
For 
D 
>> 
1 
and 
D 
= 
0(1), 
the equilibrium  location  of  a  one-spike 
solution  is given by  the zeroes of  the gradient  of  the regular  part of  the 
Neumann Green’s function and the reduced wave Green’s function, respec- 
tively. In this way, we  examine how both the shape of  the domain and the 
inhibitor diffusivity 
D 
determine the possible equilibrium  locations  for  a 
one-spike solution.  For 
D 
small, we  find that stable equilibrium spike loca- 
tions tend to the centers of  the disks of  largest radii that can 
fit 
within the 
domain. Hence, for 
D 
small, there are two stable equilibrium locations for 
a dumbbell-shaped  domain. In contrast, from the Neumann  Green’s func- 
tion, we  predict that for 
a 
family of  dumbbell-shaped domains there is only 
one possible equilibrium location when 
D 
is sufficiently large.  This change 
in the multiplicity of  an equilibrium spike-layer location is explained from 
a 
certain bifurcation  behavior of  the zeroes of  the gradient of  the regular 
part of  the reduced wave Green’s function that occurs 
at 
a 
certain critical 
value of 
D. 
The results below have been derived in 
[54] 
and 
[55]. 
There have been 
very few analytical studies of  the dynamics of  spikes for the GM model (1.1) 
or for other reaction-diffusion systems in 
R2. 
In 
[15] 
and [lo31 the motion 
of 
a 
one-spike solution for the GM model 
(1.1) 
was studied for 
D 
>> 
1. In 
[34] the metastable motion of  a two-spike solution in 
R2 
was studied in the 
weak interaction limit where 
D 
= 
O(E~). 
This problem is equivalent to a 
one-spike solution in 
a 
half-space with a Neumann boundary condition. For 
this case, the spike interaction is repulsive, 
as 
was found in [34]. 
In the results below, there are two Green’s functions that play 
a 
promi- 
nent role. The reduced wave Green’s function 
G(z; 
zo) 
satisfies 
1 
D 
AG 
- 
-G 
= 
-d(z 
- 
ZO) 
, 
z 
E 
R; 
&G 
= 
0, 
z 
E 
do. 
(4.1) 
The regular part 
R(z; 
20) 
of  this function is defined by