287
References
Arlaud GJ, Colomb MG & Gagnon J (1987) A Functional model of
the human C1 complex. Immunol. Today 8: 106–111.
Bock SC, Skriver K, Nielsen E, Thogersen HC, Wiman B, Donaldson
VH, Eddy RL, Marriman J, Radziejewska E, Huber R, Shaws TB
& Magnusson S (1986) Human C1 inhibitor: primary structure,
cDNA cloning, and chromosomal localization. Biochemistry 25:
4292–4301.
Borsos T, Loos M, Chapuis RM, Medicus R & Isliker H (1980)
A novel way of relating the structure of Clq to the hemolytic
activity of the first component of complement. Mol. Immunol.
17: 1415–1421.
Coutinho M, Aulak KS & Davis AE (1994) Functional analysis of
the serpin domain of C1-inhibitor. J. Immunol. 154: 3648–3654.
Davidson DJ & Castellino FJ (1991) Asparagine-linked oligosac-
charidc processing in Lepidopteran insect cells. Temporal depen-
dence of the nature of the ologosaccharides assembled on
Asparagine-289 of recombinant human plasminogen produced
in baculovirus vector infected Spodoptera frugiperda (IPLB-SF-
21AE) cells. Biochemistry 30: 6167–6174.
Dobó .J (1993) Diploma thesis. Institute of Enzymology, Budapest.
Donaldson VH & Evans RR (1963) A biochemical abnormality in
hereditary angioneurotic edema: absence of serum inhibitor of
Cl-esterase, Am. J. Med. 35: 37–44.
Eldering E, Nuijens JH & Hack C (1988) Expression of functional
human C1 inhibitor in COS cells. J. Biol. Chem. 263: 11776–
11779.
Gál P, Sárvári M, Szilágyi K, Závodszky P & Schumaker VN (1989)
Expression of hemolytically active human complement compo-
nent C1r proenzyme in insect cells using a baculovirus vector.
Complement and Inflammation. 6: 433–441.
Gál P, Cseh S, Schumaker VN & Zádvodszky P (1994) The structure
and function of the first component of complement: genetic engi-
neering approach. Acta Microbiol. Immunol. Hung. 41: 361–380.
Hajós J (1993) Diploma thesis. Institute of Enzymology, Budapest.
Knobel HR, Villiger W & Isliker H (1975) Chemical analysis and
electron microscopy studies of human Clq prepared by different
methods. Eur. J. Immunol. 5: 78–82.
Kuroda K, Geyer H, Geyer R, Doerfler W & Klenk HD (1990) The
oligosaccharides of influenza virus hemagglutinin expressed in
insect cells by a baculovirus vector. Virology 174: 418–429.
Leytus SP, Kurachi K, Sakariassen S & Davie EW (1986) Nucleotide
sequence of cDNA coding for human complement C1r. Biochem-
istry 25: 4855–4863.
Luo C, Thielens NM, Gagnon J, Gál P, Sárvári M, Tseng Y,
Tosi M, Závodszky P, Arlaud GJ & Schumaker VN (1992)
Recombinant human complement subcomponent C1s lacking
hydroxyasparagine, sialic acid, and one of its two carbohydrate
chain still reassembles with C1q and C1r to form a functional
complex. Biochemistry 31: 4254–4262.
Mackinnon CM, Carter PE, Smyth SJ, Dunbar B & Fothergill JE
(1987) Molecular cloning of cDNA for human complement com-
ponent Cls. The complete amino acid sequence. Eur. J. Biochem.
169: 547–553.
Monkovic DD, VanDusen VJ, Petroski CJ, Garski VM, Sardana
MK, Závodszky P, Stern AM & Friedman PA (1992) Inverte-
brate aspartyl/asparaginyl hydroxylase: potential modification
of endogeneous epidermal growth factor-like modules. Biochem.
Biophys. Res. Comm. 189: 233–241.
Patthy L (1994) Modular design of proteases of coagulation, fib-
rinolysis, and complement activation: implications for protein
engineering and structure-function studies. In: Lorand L & Mann
KG (ed.) Methods in Enzymology. Vol. 222 (pp. 10–22) Acad-
emic Press, New York.
Petry F, Reid KBM & Loos M (1989) Molecular cloning and char-
acterization of the complementary DNA coding for the B-chain
of murine Clq. FEBS Lett. 258: 89–93.
Petry F, Reid KBM & Loos M (1991) Gene expression of the A- and
B-chain of mouse C1q in different tissue and the characterization
of the recombinant A-chain. J. Immunol. 147: 3988–3993.
Petry F, Reid KBM & Loos M (1992) Isolation, sequence analysis
and characterization of cDNA clones coding for the C chain of
mouse C1q. Eur. J. Biochem. 209: 129–134.
Przysiecki CT, Staggers JR, Ramjit HG, Mussan DG, Stern
AM, Bennett CD & Friedman PA (1987) Occurrence of
hydroxylated asparagine residues in non-vitamin K dependent
proteins containing epidermal growth factor-like domains. Proc.
Natl. Acad. Sci. 84: 7856–7860.
Rapp HJ & Borsos T (1970) Molecular basis of complement action.
Meredith Corporation, New York.
Reid KBM & Porter RR (1976) Subunit composition and structure of
subcomponent C1q of the first component of human complement.
Biochem J. 155: 19–23.
Sárvári M, Csikós Gy, Sass M, Gál P, Schumaker VN & Závodszky
P (1990) Ecdysteroids increase the yield of recombinant protein
produced in baculovirus insect cell expression system. Biochem.
Biophys. Res. Comm. 167: 1154–1161.
Schumaker VN, Závodszky P & Poon P (1987) Activation of the
first component of complement. Ann. Rev. Immunol. 5: 21–42.
Schumaker VN, Tseng Y, Poon PH, Bianchino AC & Závodszky
P (1989) Spontaneous activation of reconstituted and serum Cl
and the role of Cl-inhibitor. Behring Institute Mitteilungen 84:
102–110.
Sellar GC, Blake DJ & Reid KBM (1991) Characterization and
organization of the genes encoding the A-, B- and C chains of
human complement subcomponent Clq. Biochem. J. 274: 481-
490./
Stenflo J, Lundwall A & Dahlback B (1987) Hydroxyasparagine
in domains homologous to the epidermal growth factor precursor
in vitamin K-dependent proteins. Proc. Natl. Acad. Sci. 84: 368–
372.
Summers MD & Smith GE (1987) A manual of methods for bac-
ulovirus vectors and insect cell culture procedures. Tex. Agric.
Exp. Stn., Bull., 1555, College Station, Texas.
Thim L, Bjoern S, Christensen M, Nicolaisen EM, Lund-Hansen
T, Pedersen AH & Hedner U (1988) Amino acid sequence and
posttranslational modifications of human factor from plas-
ma and transfected baby hamster kidney cells. Biochemistry 27:
7785–7793.
Tosi M, Duponchel C, Meo T & Julie C (1987) Complete cDNA
sequence of human complement C1s and close physical linkage
of the homologous genes C1s and C1r. Biochemistry 26: 8516–
8524.
Thielens NVM, Van Dorsselaer A, Gagnon J & Arlaud GJ (1990)
Chemical and functional characterization of fragment of C1s con-
taining the epidermal growth factor homology region. Biochem-
istry 14: 3570–3578.
Tschopp J, Villiger W, Fuchs H, Kilcherr E & Engel J (1980) Assem-
bly of subcomponents C1r and C1s of the first component of com-
plement: electron microscope and ultracentrifugal studies. Proc.
Narl. Acas. Sci. 77: 7014–7019.
Tseng Y, Poon PH, Závodszky P & Schumaker VN (1991) Spon-
taneous activation of serum C1 in vitro. Role of C1 inhibitor. J.
Immunol. 147: 1884–1890.