Kluwer Academic/Plenum Publishers, New York, 2005, Pages: 291
In Viral Membrane Proteins: Structure, Function, and Drug Design, Wolfgang Fischer summarizes the current structural and functional knowledge of membrane proteins encoded by viruses. In addition, contributors to the book address questions about proteins as potential drug targets. The range of information covered includes signal proteins, ion channels, and fusion proteins.
This book has a place in the libraries of researchers and scientists in a wide array of fields, including protein chemistry, molecular biophysics, pharmaceutical science and research, bioanotechnology, molecular biology, and biochemistry.
The first section is dedicated to viral membrane proteins from plant viruses with the most recent computational research on the viral genome revealing the first experimental evidence of a K+ channel encoded by a plant virus. The second section in the book is dedicated to the proteins involved in the early event of the life cycle of the viruses in the host cell, the fusion proteins. The third section summarizes, in several chapters, the current state of the research on ion channels and viroporins, which are known to modulate the electrochemical balance in the virus itself and subcellular compartments in the host cell. The fourth section describes membrane-bound and membrane-associated viral proteins. All chapters include functional and structural data and address, where possible, the development of antiviral drugs. A large number of techniques are described by the authors, revealing the way in which a wide range of approaches are required to shed light on the molecular life of viruses.
In Viral Membrane Proteins: Structure, Function, and Drug Design, Wolfgang Fischer summarizes the current structural and functional knowledge of membrane proteins encoded by viruses. In addition, contributors to the book address questions about proteins as potential drug targets. The range of information covered includes signal proteins, ion channels, and fusion proteins.
This book has a place in the libraries of researchers and scientists in a wide array of fields, including protein chemistry, molecular biophysics, pharmaceutical science and research, bioanotechnology, molecular biology, and biochemistry.
The first section is dedicated to viral membrane proteins from plant viruses with the most recent computational research on the viral genome revealing the first experimental evidence of a K+ channel encoded by a plant virus. The second section in the book is dedicated to the proteins involved in the early event of the life cycle of the viruses in the host cell, the fusion proteins. The third section summarizes, in several chapters, the current state of the research on ion channels and viroporins, which are known to modulate the electrochemical balance in the virus itself and subcellular compartments in the host cell. The fourth section describes membrane-bound and membrane-associated viral proteins. All chapters include functional and structural data and address, where possible, the development of antiviral drugs. A large number of techniques are described by the authors, revealing the way in which a wide range of approaches are required to shed light on the molecular life of viruses.