Биологические дисциплины
Академическая и специальная литература
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Klipp E., Herwig R., Kowald A., Wierling C., Lehrach H. Systems Biology in Practice: Concepts, Implementation and Application
Wiley-VCH, 2005, Pages: 486

Presenting the main concepts, this book leads students as well as advanced researchers from different disciplines to an understanding of current ideas in the complex field of comprehensive experimental investigation of biological objects, analysis of data, development of models, simulation, and hypothesis generation.

This book is divided into three parts. The first part gives an introduction to three main foundations of systems biology – cell biology, mathematics, and experimental techniques. This will be very basic for advanced readers but will prove helpful for those approaching systems biology from a different scientific discipline.
The second part of the book presents current strategies of computational modeling and data mining. It covers in detail various cellular processes such as metabolism, signaling, the cell cycle, and gene expression, as well as the interactions between them. We introduce different concepts of modeling and discuss how the different models can be used to tackle a number of frequent problems, including such questions as how regulation is organized, how data can be interpreted, or which model to apply under specific settings.
The third part gives an overview on currently available help and resources from the Inteet. We represent modeling tools that we frequently use ourselves. We also give an overview on databases that are indispensable for information exchange and therefore constitute an essential support for systems biology.
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