
variety of biochemical, molecular biological and genetic techniques. The organisms ir^lud^
those that row on simple carbon sources such as carbon dioxide, methane or
alkyl
sulf::
compounds
to those that are more complex such as treptomyces and a variety of human ап(
animal
pathogens. The control of enzyme activity and gene expression is an important featun
of the research as
well
as the exploitation of many of these orga ism
for biotechnological research. The epidemiology and evolution of antibiotic production
resistance and virulence are also being examined in a
wide
range of organisms
Bacteriophages are being investigated, both in terms of their ecological and their potential fo
phage therapy.
Professor
H
Dalton:
The biochemistry and mechanism of bacterial methane activiation and ;
proteomic
approach to the study of bacterial and mammalian gene expression in
lifff^re.n
environmental conditions
DrCS
Dow: Prevalence and importance of dormancy (physiological quiescence) i)
environmental, industrial and pathogenic bacterial populations e.g. cyanobacteria, Escherichi;
coli 0157:H7, Chlamydia trachomatis and Staphylococcus aureus.
Professor
С G
Dowson:
The population
biology,
expression and evolution of resistance ап(
virulence determinants, in Streptococcus pneumoniae, the oral streptococci, Campylobacte
jejuni, Burkholderia cepacia, Listeria monocytogenes and chronic wound micro flora.
DrKP
Flint:
Survival
of indicators of faecal pollution in freshwater. The
physiology
of starve(
microorganisms. The maintenance and transfer of plasmids in starved enteric bacteria.
Dr DA
Hodgson:
The mechanism of light-induced gene expression in Myxococcus xanthus
The
mechanisms that
allow
Listeria monocytogenes to
grow
within animal cells. The cuntro
of secondary metabolism in Streptomyces coelicolor. Molecular computing.
Dr I
McDonald:
The molecular ecology of methane oxidation in extreme environments ап(
the
microbiology of the atmospheric trace
gases
methylbromide and methylchloride
Professor N H
Mann:
The biochemistry, molecular
biology
and genetics of marine am
freshwater picoplanktonic cyanobacteria and their
viruses.
Protein:protein interactions ii
thylakoid biogenesis. Phage therapy.
Professor
J С
Murrell:
Molecular
biology,
physiology,
biochemistry of methylotrophii
bacteria. Molecular ecology of
methanotrophs.
The methane cycle. Bacterial organic
sulfu
metabolism. Bioremediation/biotransformations.
DrPR
Norn's:
Study of iron- and sulphur
oxidizing micro-organisms (particularly thermophiles): their ecology,
physiology,
genetic
and
industrial application in metal recovery/biomining. *
DrDJ
Scanlan: Molecular ecology: mechanisms controlling oceanic photosynthesis in
Synechococcus and Prochlorococcus (cyanobacteria), eukaryotic phytoplankton.
Molecular genetics: nutrient acquisition & light sensing in cyanobacteria.
Professor
EMH
Wellington:
Antibiotic production in
soil
and the distribution of
antibiotic gene clusters in microbial populations.
Survival,
growth and activity of bacteria
in
soil. Horizontal gene transfer in nature and the evolution of antibiotic gene clusters.
Environmental
impacts of the use of antibiotics and the dissemination of antibiotic
resistance genes in environmental bacteria. Interactions between bacteria and amoebae in
soil
and water. Bacterial and fungal chitinases.
Molecular
Cell
Biology
This research group is using a range of cell and molecular
biology
techniques to carry out
research on higher plants, mammalian
cells
and
yeast.
Particular attention is focused on
the
entry of proteins into chloroplasts, molecular mechanisms of circadian rhythms in
higher plants and
yeast,
proteins
involved
in photosynthesis, plant and bacterial proteins