
Environmental Encyclopedia 3
Homeostasis
hypothalamus, causes the anterior pituitary to release thyroid
stimulating hormone which, in turn, causes the thyroid gland
to increase production of thyroxine which results in increased
metabolism
and therefore heat. Sympathetic nerves from
the hypothalamus stimulate the adrenal medulla to secrete
epinephrine and norepinephrine into the blood which also
increases body metabolism and heat. Increased muscle activ-
ity will generate heat and that activity can be either voluntary
(stamping the feet for instance) or involuntary (shivering).
Since heat is dissipated via body surface blood vessels, the
nervous system causes surface vasoconstriction to decrease
that heat loss. Further, the small quantity of blood that does
reach the surface of the body, where it is chilled, is reheated
by countercurrent heat exchange resulting from blood vessels
containing cold blood from the limbs running adjacent to
blood vessels from the body core which contain warm blood.
The chilled blood is prewarmed prior to returning to the
body core. A little noted response to chilling is the voluntary
reaching for a jacket or coat to minimize heat loss.
The body responds with opposite results when exces-
sive heat is encountered. The individual tends to shed unnec-
essary clothing, and activity is reduced to minimize metabo-
lism. Vasodilation of superficial blood vessels allows for
radiation of heat. Sweat is produced, which by evaporation
reduces body heat. It is clear that the maintenance of body
temperature is closely controlled by a complex of homeostasis
mechanisms.
Each step in temperature regulation is controlled by
negative feedback. As indicated above, with exposure to cold
the hypothalamus, through a series of steps, induces the
synthesis and release of thyroxine by the thyroid gland. What
was not indicated above was the fact that elevated levels of
thyroxine control the level of activity of the thyroid by nega-
tive feedback inhibition of thyroid stimulating hormone. An
appropriate level of thyroid hormone is thus maintained. In
contrast, with inadequate thyroxine, more thyroid stimulat-
ing hormone is produced. Negative feedback controls assure
that any particular step in homeostasis does not deviate too
much from the normal.
Historically, biologists have been particularly impres-
sed with mammalian and human homeostasis. Lower verte-
brates have received less attention. However, while internal
physiology may vary more in a frog than in a human, there
are mechanisms which assure the survival of
frogs
. For
instance, when the ambient temperature drops significantly
in the autumn in northern latitudes, leopard frogs move into
lakes or rivers which do not freeze. Moving into lakes and
rivers is a behavioral response to a change in the external
environment which results in internal temperature stability.
The metabolism and structure of the frog is inadequate to
protect the frog from freezing, but the specific heat of the
water is such that freezing does not occur except at the
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surface of the overwintering lake or river. Even though life
at the bottom of a lake with an ice cover moves at a slower
pace than during the warm summer months, a functioning
circulatory system is essential for survival. In general, frog
blood (not unlike crankcase oil prior to the era of multiviscos-
ity oil) increases in viscosity with as temperature decreases.
Frog blood, however, decreases in viscosity with the pro-
longed autumnal and winter cold temperatures, thus assuring
adequate circulation during the long nights under an ice
cover. This is another control mechanism that assures the
survival of frogs by maintaining a relatively stable internal
environment during the harsh winter. With a return of a
warm external environment, northern leopard frogs leave
cold water to warm up under the spring sun. Warm tempera-
ture causes frog blood viscosity to increase to summer levels.
It may be that the behavioral and physiological changes do
not prevent oscillations that would be unsuitable for warm
blooded animals but, in the frog, the fluctuations do not
interfere with survival, and in biology, that is all that is
essential.
There is homeostasis in ecological systems. Popula-
tions of animals in complex systems fluctuate in numbers,
but the variations in numbers are generally between limits.
For example, predators survive in adequate numbers as long
as prey are available. If predators become too great in num-
ber, the population of prey will diminish. With fewer prey,
the numbers of predators plummet through negative feed-
back thus permitting recovery of the preyed upon species.
The situation becomes much more complex when other food
sources are available to the predator.
Many organisms encounter a negative feedback on
growth rate with crowding. This density dependent popula-
tion control has been studied in larval frogs, as well as many
other organisms, where excretory products seem to specifi-
cally inhibit the crowded species but not other organisms in
the same environment. Even with adequate food, high den-
sity culture of laboratory mice results in negative feedback
on reproductive potential with abnormal gonad development
and delayed sexual maturity. Density independent factors
affecting populations are important in population control
but would not be considered homeostasis.
Drought
is such
a factor, and its effects can be contrasted with crowding.
Populations of tadpoles will drop catastrophically when
breeding ponds dry. Instead of fluctuating between limits
(with controls), all individuals are affected the same (i.e.,
they die). The area must be repopulated with immigrants
at a subsequent time, and the
migration
can be considered
a population homeostatic control. The inward migration
results in maintenance of population within the geographic
area and aids in the survival of the species.
[Robert G. McKinnell]