
STEP 5: PEARLS AND PITFALLS
◆ The Graham closure of a perforated peptic ulcer is usually a highly effective and effi cient
way of controlling the perforation site.
◆ A well-vascularized pedicle of omentum must be selected and approximated under no
tension.
◆ If the patient has a history of chronic ulcer disease that has been unsuccessfully treated
with medical management, a more defi nitive ulcer operation, such as a truncal vagotomy
and pyloroplasty, should be performed depending on the amount of contamination in
the abdominal cavity and the duration of the perforation. However, as noted previously,
the current medical regimens for ulcer treatment have greatly diminished the need for a
defi nitive operation at the time of ulcer closure.
◆ The abdomen should be copiously irrigated with saline to decrease the chances of intra-
abdominal abscess forming after the procedure.
SELECTED REFERENCES
1. Mercer DW, Robinson EK: Stomach. In Townsend CM Jr (ed): Sabiston Textbook of Surgery: The Biologi-
cal Basis of Modern Surgical Practice, 18th ed. Philadelphia, Saunders, 2008, pp 1223-1277.
2. Thompson JC: Perforation of duodenal ulcer: Treatment by simple closure or by closure plus acid-
reducing operation. In Thompson JC (ed): Atlas of Surgery of the Stomach, Duodenum and Small
Bowel. St Louis, Mosby-Year Book, 1992, pp 113-119.
CHAPTER 29 • Open and Laparoscopic Closure of Perforated Peptic Ulcer 323